Dear visitor,
first time, detailed antibiotic inhibitory data of
licensed drugs of the major markets of Europe, Japan and
USA is available in one data system via the internet.
The database was named AmicBase
Drugs-Online 2011
and is published for information and educational
purposes.
AmicBase Drugs-Online is free - even a registration is not
required
!
Start here.
Antibiotics are essential for the treatment of infectious diseases.
However, microbial resistances had developed against
many drugs. To
improve the situation not only new antibiotic
developments are necessary also providing existing
information on available drugs, their activities and
microbial resistances is an important progress.
In AmicBase Drugs-Online 2011
information on over 600 licensed drugs
having
antimicrobial activity (antibiotics, antimycotics,
antiseptics) is saved in over 79.000 documents. The
database displays their trade names plus the countries, in which the trade names are in
use, respectively. The number of microorganisms saved in the
drugs
database exceeds the number of 1.500. It is
understandable, that a computer information system is
needed to overlook the data situation. To arrange such
information was another task to be solved, since various
microbiological testing systems exist and, e.g.,
inhibitory concentrations are given in different formats
and units.
Some more details, such as abbreviations used, statistics, standardization procedures and
more, are given in the
manual.
In November 2011 about 9.300 data records on clinical
breakpoints (MIC, inhibition zones) and susceptibility
of pathogenic wild type microbial strains were added to
AmicBase Drugs-Online from EUCAST (European Committee on
Antimicrobial Susceptibility Testing)
data collection with permission . This allows data viewing of
drugs having defined clinical breakpoints and comparison
to data of drugs without having such definitions. In
many cases activity ranges of a given drug towards
pathogenic microbial species are displayed, which
provide
professionals a quick information on obtained lab
results.
Revival
of antibiotics, such as
temocillin, indicate the importance of sharing knowledge
(reference,
antibiotic spectrum). Recently, two fatal cases of
ESBL Escherichia coli infections are reported -
answering some natural questions would be desirable.
Read more ...
AmicBase Drugs-Online
2011 derives from AmicBase 2006, which is the update of
AmicBase 2005
(ISBN 0471743925). The 2005 version became
temporarily a
product of John Wiley & Sons. Previous versions (1999
to
2004) have
been marketed by ReviewScience (Germany), the former
company of the author of AmicBase, Dr. Alexander Pauli.
To complete the information on AmicBase, the
current version has 200.700 data records dating from the
year 2006. It
displays therapeutic indices being calculated from
microbiological inhibitory data and several kind of
toxicological data. It is searchable for chemical
structures and substructures combined with numeric or
text searches (see
Manual 2006). AmicBase 2006 is actually not
available.
AmicBase Drugs-Online
Linkage:
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Advisory Group on
Integrated Surveillance
of Antimicrobial
Resistance (AGISAR)
World Health
Organization
European
Committee on
Antimicrobial
Susceptibility Testing (EUCAST)
European Society for
Clinical Microbiology
and Infectious Diseases
National
Center for
Biotechnology Information
(NCBI)
PubChem:
find
chemical structures
of AmicBase Drugs-Online,
e.g. "770"[sourcename]
penicillin finds
penicillins
Taxonomy Browser:
search
microbial species of
AmicBase Drugs-Online
National Library of
Medicine, National
Institutes of Health,
USA
European Course
in Medical Device Regulation
ECPM Institute of
Pharmaceutical Medicine,
University of Basel,
Switzerland
European Center for
Pharmaceutical Medicine
European Confederation
of the Upper Rhine
Universities Basel,
Freiburg i.Br. and
Strasbourg
Robert Koch-Institute, (RKI)
Bundesministerium für
Gesundheit, Berlin, Germany
Alianza para el Uso Prudente de los Antibioticos, (APUA-CUBA)
Infomed-Centro Nacional de Información de Ciencias Médicas, MINSAP, Cuba
Conselho Nacional da
Pecuária de Corte
(CNPC)
Brazilian National Bees
Cattle Counclil,
Brazil
Polish Academy of
Sciences (PAN)
Instytucja Naukowa,
Poland
Asistanhekim
Turkish Physician Portal,
Turkey
Complejo Hospitalario La
Mancha Centro
Alcázar de San Juan,
Spain
Microbe World
(among top 100 messages
2011)
American Society for
Microbiology,
USA
Society for Medicinal
Plant and Natural
Product Research
Gesellschaft für
Arzneipflanzen- und
Naturstoff-Forschung,
Germany
Pharmazeutische Zeitung
Online,
Arzneimittelinformationen
Die Zeitschrift der
Deutschen Apotheker
(Eschborn, Germany)
iSpecies.org:
a Species Search Engine
News arcives:
South American Infectious Diseases Initiative
(SAIDI),
Southern African Centre for Infectious Disease
Surveillance (SACIDS),
Bacteriamuseum,
Febril Nötropeni,
WIKIO News,
Pharmaceutical Microbiology,
ZIMBIO,
Medical Laboratory and
EQAS News
Press:
Communication of
antibiotic knowledge -
free online support for
physicians (L'Italo Euopeo,
London, UK,
Aug. 2011),
Doktor Paulis
Kamillenträume
(Nürnberger Zeitung,
Nürnberg, Germany, Oct.
2008)
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30. Nov. 2011 actualized
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